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Methotrexate - Meaning, Definition & English Examples

Methotrexate is a medication used to treat certain cancers, autoimmune diseases, and severe psoriasis. It works by slowing cell growth and reducing inflammation in the body.

methotrexate

/ˌmɛθəˈtrɛkseɪt/ /ˌmɛθəˈtrɛkseɪt/

Definition:

A chemotherapy drug and immune system suppressant used to treat cancer and autoimmune diseases.

Synonyms:

amethopterin, MTX, Rheumatrex, Trexall

Part of Speech:

noun

Antonyms:

(No direct antonyms; context-dependent)

Common Collocations:

high-dose methotrexate, methotrexate therapy, methotrexate injection, methotrexate side effects

Derivatives:

methotrexate sodium, methotrexate-resistant

Usage Tips:

Use "methotrexate" when discussing chemotherapy or autoimmune treatments; specify dosage and condition for clarity.

Common Phrases:

(No common phrases or idioms; highly specialized term)

Etymology:

Derived from "methyl" and "trexate," reflecting its chemical structure and function as a folate antagonist.

Examples:

  • 1. Methotrexate is prescribed for rheumatoid arthritis.
  • 2. The oncologist adjusted her methotrexate dosage.
  • 3. Methotrexate can cause nausea and fatigue.
  • 4. Patients must monitor liver function while taking methotrexate.

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